GR (Acetyl Lys494) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis This intronless gene has several

This intronless gene has several pseudogenes spread throughout the genome

The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain

It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity

The encoded protein is a member of the IL10 family of cytokines

and is thought to be subsequently degraded

GR (Acetyl Lys494) Rabbit Polyclonal Antibody, 20ul DNA Libraries Synthesis This intronless gene has severalalternative products: At least 4 isoforms Alpha (shown here) Alpha B Beta and Beta B are produced by alternative initiation at Met 1 and Met 27. The existence of isoform Alpha and isoform Alpha B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms alternative initiation of translation could also occur on these transcripts. Additional isoforms seem