KLF13 Polyclonal Antibody, 100ul Low-speed Centrifuges Activation of T cells increased

Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold

suggesting a role in the regulation of DNA replication

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck

Glycosylation is necesssary for proper targeting of the transporter to the plasma membrane

similar to Vps4 protein in yeast

KLF13 Polyclonal Antibody, 100ul Low-speed Centrifuges Activation of T cells increasedKLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes (Scohy et al. 2000 [PubMed: 11087666]).