Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies Diseases associated with C2orf40 include

Diseases associated with C2orf40 include esophageal cancer

This gene is highly expressed in testis and spleen

Directly mediates protection against viral and bacterial genital infections (By similarity)

Mutations in GDI1 have been linked to X-linked nonspecific mental retardation

This gene and FGF3

Rb Polyclonal Antibody, 20ul[BT-AP07691] Primary Antibodies Diseases associated with C2orf40 includeThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.