NMS-1286937 Catalog No.:M9125-2 InChi: InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H

InChi: InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H

Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4

Chemical Name: Salinomycin sodium salt

cell-permeable γ-secretase inhibitor (IC50= 0

3 nM and LRRK2-[G2019S] ~3

NMS-1286937 Catalog No.:M9125-2 InChi: InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12HOnvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1