SB 239063 - CAS# 193551-21-2 zone Maleate Ther Deliv

Ther Deliv

InChiKey: LOLHUPGCPDURJG-UHFFFAOYSA-N

(S)-2-(1-((2-amino-9H-purin-6-yl)amino)ethyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one hydrochloride

whereas both PI3Kα and -β were relatively unaffected (IC50 values>1 μM)

selective and ATP-competitive mTOR inhibitor (IC50 = 2

SB 239063 - CAS# 193551-21-2 zone Maleate Ther DelivSB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin 1 and tumor necrosis factor alpha production (IC(50) values = 0. 12 and 0. 35 microM, respectively). SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Product information CAS Number: 193551 21