AZ3146 WP L6 Protopine is a naturally occuring

Protopine is a naturally occuring benzylisoquinoline alkaloid found in plants of the family papaveraceae It acts as an analgesic and can inhibit histamine H1 receptors

Chemical Name: 5-{2-[4-(1

Norimatsu Y

VLX1570 has potent antiproliferative activities on multiple myeloma cells

identified by a high-throughput

AZ3146 WP L6 Protopine is a naturally occuringAZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full length Mps1 immunoprecipitated from human cells. Product information CAS Number: 1124329 14 1 Molecular