WH-4-023 Size:Solid 10 mg 6]tricos-16-ene-3

6]tricos-16-ene-3

IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma

4-c]pyridine-3-carboxamide

1136/bjophthalmol-2012-302466

12 dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinoma

WH-4-023 Size:Solid 10 mg 6]tricos-16-ene-3WH 4 023 is a potent and selective dual Lck Src inhibitor with IC50 of 2 nM 6 nM for Lck and Src kinase respectively. The lymphocyte specific kinase ( Lck ) is a cytoplasmic tyrosine kinase of the Src family expressed in T cells and NK cells. Genetic evidence in both mice and humans demonstrates that Lck kinase activity is critical for signaling mediated by the T cell receptor (TCR), which leads to normal T cell development and activation. Product