CFTR Inhibitor II(GlyH101) - CAS# 328541-79-3 273 Extensive biochemical

Extensive biochemical

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effectively clearing the receptor from the cell surface and selectively inhibiting intracellular signaling (IC50 0

CFTR Inhibitor II(GlyH101) - CAS# 328541-79-3 273 Extensive biochemicalCFTR Inhibitor II, CAS No. 328541 79 3, is a CFTR inhibitor (cystic fibrosis transmembrane conductance regulator). CFTR Inhibitor II is a glycine hydrazide that has been shown to block CFTR channels. CFTR Inhibitor II blocked I(Cl. PKA) in a concentration and voltage dependent fashion (IC(50) at +100 mV=0. 3 1. 5 M and at 100 mV=5. 1 1. 3 M). CFTR Inhibitor II blocks the open pore of cardiac CFTR channels at an electrical distance of 0. 15 0. 03 from