SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Major Depressive Disorder and Kappa

Major Depressive Disorder and Kappa Opioid Receptor Antagonists

Smiles: CC1(C)C=CC2=CC(CCN3C4=CC=CC=C4C4=CC=CC=C34)=CC(C=O)=C2O1

PubMed PMID: 26331795

Formula: C9H16Br2N5O4P

InChi: InChI=1S/C23H19NO3/c1-26-17-11-7-15(8-12-17)21(16-9-13-18(27-2)14-10-16)22-19-5-3-4-6-20(19)24-23(22)25/h3-14H

SC-79 - CAS# 305834-79-1 Catalog No.:M6552-2 Major Depressive Disorder and KappaSC 79, CAS No. 305834 79 1, is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC 79 is a potential treatment for alcohol induced osteonecrosis of the femoral head. SC 79 injections inhibited alcohol induced osteonecrosis. Alcohol induced ONFH is associated with suppression of p Akt Ser473 in the Akt GSK3 catenin signaling pathway in bone mesenchymal stem cells.