PI3K-IN-1 uxadoline AMPK α2β1γ1

AMPK α2β1γ1

CAS Number: 101831-37-2

Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R

PubMed PMID: 27074538

Formula: C28H34Cl2F2N2O

PI3K-IN-1 uxadoline AMPK α2β1γ1Voxtalisib, also known as XL 765 and SAR245409, is a PI3K mTOR dual kinase inhibitor XL765 is an orally bioavailable small molecule targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K mTOR signaling pathway, with potential antineoplastic activity. PI3K mTOR dual kinase inhibitor XL765 inhibits both PI3K kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in