SF-1670 - CAS# 345630-40-2 30001 the 50 mg/kg dose was

the 50 mg/kg dose was decreased to 30 mg/kg

CAS Number: 915087-33-1

DNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survival

18(15):4388-92

Smiles: CC1=CC(O)=C(C2=C1NC(=O)C1SC=CC=12)C1C=CC(=CC=1)[C@@H](C)CN

SF-1670 - CAS# 345630-40-2 30001 the 50 mg/kg dose wasSF 1670, CAS No. 345630 40 2, is a specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor. SF 1670 specifically binds to the active site of PTEN inhibiting its activity with an IC50 value of 2 M. The innate immune responses can be enhanced and the severity of neutropenia related infection can be alleviated by augmenting phosphatidylinositol (3, 4, 5) trisphosphate in transfused neutrophils with PTEN inhibitor SF 1670,