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JX06 Catalog No.:M7378-2 Smiles: CC1C=CC(=CC=1)C1N=C(CSC2=NN=C(C3C=CN=CC=3)N2C2C=CC(=CC=2)OC)ON=1

JX06 Catalog No.:M7378-2 Smiles: CC1C=CC(=CC=1)C1N=C(CSC2=NN=C(C3C=CN=CC=3)N2C2C=CC(=CC=2)OC)ON=1

Name: JX06 Catalog No.:M7378-2 Smiles: CC1C=CC(=CC=1)C1N=C(CSC2=NN=C(C3C=CN=CC=3)N2C2C=CC(=CC=2)OC)ON=1
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SKU: 61916673095
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SKU: 61916673095

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JX06 Catalog No.:M7378-2 Smiles: CC1C=CC(=CC=1)C1N=C(CSC2=NN=C(C3C=CN=CC=3)N2C2C=CC(=CC=2)OC)ON=1JX06 as a selective covalent inhibitor of PDK1 in cells. JX06 dose dependently inhibits PDK1, PDK2 and PDK3 with IC50 0. 049 M, 0. 101 M and 0. 313 M, respectively. Product information CAS Number: 729 46 4 Molecular Weight: 324. 51 Formula: C10H16N2O2S4 Chemical Name: Bis(morpholinothiocarbonyl) disulfide Smiles: S=C(SSC(=S)N1CCOCC1)N1CCOCC1 InChiKey: KKVYOWPPMNSLCP UHFFFAOYSA N InChi: InChI=1S C10H16N2O2S4 c15 9(11 1 5 13 6 2 11)17 18 10(16)12 3 7 14

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Description

Smiles: CC1C=CC(=CC=1)C1N=C(CSC2=NN=C(C3C=CN=CC=3)N2C2C=CC(=CC=2)OC)ON=1

2015 Jul 6

a multitargeted inhibitor of histone deacetylase

33(5):289-94

PD169316 abrogates signaling initiated by both TGFbeta and Activin A

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