Telotristat Catalog No.:M9043-10 108(20):8299-304

108(20):8299-304

Molecular Weight: 658

MCOPPB trihydrochloride is a potent and selective agonist of the NOP receptor

with TGI of 88% and 97%

cellular stresses and bacterial endotoxin in vivo

Telotristat Catalog No.:M9043-10 108(20):8299-304Telotristat, also known as LP 778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical and infection induced intestinal inflammation. Product