Losartan potassium Ras G12C-IN-3 PubMed PMID: 24718602
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Losartan potassium Ras G12C-IN-3 PubMed PMID: 24718602Losartan Potassium is a non peptide angiotensin II receptor antagonist with antihypertensive activity. Losartan selectively and competitively binds to the angiotensin II receptor (type AT1) and blocks the binding of angiotensin II to the receptor, thus promoting vasodilatation and counteracting the effects of aldosterone. Converted from angiotensin I by angiotensin converting enzyme (ACE), angiotensin II stimulates the adrenal cortex to synthesize and
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