CP-690550 - JAK Inhibitor. CAS# 477600-75-2 0273 is a selective Rev-Erbα/β agonist

is a selective Rev-Erbα/β agonist that increases wakefulness

Su-11274 increases tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation

ETH 2120 ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment

suggesting potentially a long-lasting effect of S3I-201 on tumor growth

a potent and selective inhibitor of polo-like kinase 1

CP-690550 - JAK Inhibitor. CAS# 477600-75-2 0273 is a selective Rev-Erbα/β agonistCP 690550, CAS No. 477600 75 2, is a potent and selective JAK inhibitor currently in clinical trials for rheumatoid arthritis (RA) and other autoimmune disease indications. It inhibits recombinant human JAK1 (IC50 ~ 3. 2 nM), JAK2 (IC50 ~4. 1 nM), and JAK3 (IC50 ~1. 6 nM). In cellular assays CP 690550 showed potent effects in the IL 2 blast proliferation assay (IC50 ~11 nM, mediated via JAK1 and JAK3) and HU03 cellular specificity assay (IC50 ~324 nM,