DK419 - CAS# 2102672-22-8 Catalog No.:M6956-10 Bacteriochlorophyll from Rhodopseudomonas sphaeroides

Bacteriochlorophyll from Rhodopseudomonas sphaeroides

is a serine/threonine kinase crucial in the regulation of mitosis

is a potent inhibitor of class I PI3K kinases with an IC50 of 19 nM

3-OH-C12 and 6-OAU increased the secretion of IL-8 from LPS-stimulated PMNs

InChi: InChI=1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12

DK419 - CAS# 2102672-22-8 Catalog No.:M6956-10 Bacteriochlorophyll from Rhodopseudomonas sphaeroidesDK419, CAS No. 2102672 22 8, is a potent inhibitor of Wnt catenin signaling and colorectal cancer growth. DK419 inhibited Wnt catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally. Product information CAS Number: 2102672 22 8