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JW 55 nspiride Hydrochloride Smiles: OC1=CC2OC(=O)SC=2C=C1

JW 55 nspiride Hydrochloride Smiles: OC1=CC2OC(=O)SC=2C=C1

Name: JW 55 nspiride Hydrochloride Smiles: OC1=CC2OC(=O)SC=2C=C1
Brand: aashay.com.au
SKU: 51839411971
Price: 101.15 USD
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SKU: 51839411971

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JW 55 nspiride Hydrochloride Smiles: OC1=CC2OC(=O)SC=2C=C1JW55 is a tankyrase 1 and tankyrase 2 (TNKS1 2) inhibitor. JW55 functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1 2), regulators of the catenin destruction complex. Inhibition of TNKS1 2 poly(ADP ribosyl)ation activity by JW55 led to stabilization of AXIN2, a member of the catenin destruction complex, followed by increased degradation of catenin. In a dose dependent manner, JW55 inhibited canonical Wnt signaling in

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Description

Smiles: OC1=CC2OC(=O)SC=2C=C1

CAS Number: 117570-53-3

and also blocks autophagosome formation

The in vitro metab

PF-03716556 is highly selective for H+

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