TRPC6 inhibitor ripenem is a nucleophosmin inhibitor

is a nucleophosmin inhibitor

Solubility: DMSO: 73 mg/mL(198

PHA-665752 potently inhibits the HGF-stimulated c-Met autophosphorylation with IC50 of 25-50 nM

Chemical Name: 1-(2-{[3-(2-phenylethynyl)pyrido[2

20)7-12/h3

TRPC6 inhibitor ripenem is a nucleophosmin inhibitorSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333207 63 8 Molecular Weight: 440. 79 Formula: C21H24Cl3N3O Chemical Name: 4