Frentizole oposide Na+/K+ ATPase inhibition increases intracellular
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Frentizole oposide Na+/K+ ATPase inhibition increases intracellularFrentizole, also known as LY 53616, is an immunosuppressive agent. Frentizole was more effective in suppressing human lymphocytes responding to Con A and PWM, than it was in cells activated by PHA, specific antigen, or alloantigen. Methylprednisolone, on the other hand, was more inhibitory for cells stimulated by PHA, specific antigen, or alloantigen. Frentizole, even at super immunosuppressive doses, does not predispose the hose (mice) to Pseudomonas
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