D-Sphingosine - CAS# 123-78-4 Catalog No.:M6801-2 Fatty acid amide hydrolase inhibitors:

Fatty acid amide hydrolase inhibitors: a patent review (2009 - 2014)

Regulation of circadian behavior and metabolism by synthetic REV-ERB agonists

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2011 Nov 8

D-Sphingosine - CAS# 123-78-4 Catalog No.:M6801-2 Fatty acid amide hydrolase inhibitors:D Sphingosine, CAS No. 123 78 4, is formed primarily from the breakdown of ceramide. Sphingosine inhibits protein kinase C and phosphatidic acid phosphohydrolase. D sphingosine, a lipid possessing the same hydrophobic base as ceramide but without a carbohydrate residue, efficiently blocked this glycolipid antigen presentation both in vitro and in spinal cords of EAE mice, and significantly decreased IL 17 and ameliorated the pathological symptoms.