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AHU-377 hemicalcium salt - CAS# 1369773-39-6 Catalog No.:M6489-2 Targeting the multiple myeloma hypoxic

AHU-377 hemicalcium salt - CAS# 1369773-39-6 Catalog No.:M6489-2 Targeting the multiple myeloma hypoxic

Name: AHU-377 hemicalcium salt - CAS# 1369773-39-6 Catalog No.:M6489-2 Targeting the multiple myeloma hypoxic
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AHU-377 hemicalcium salt - CAS# 1369773-39-6 Catalog No.:M6489-2 Targeting the multiple myeloma hypoxicAHU 377 hemicalcium salt, CAS No. 1369773 39 6, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.

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Description

Targeting the multiple myeloma hypoxic niche with TH-302

Mendelson DS

tolerability

is a novel first in class

8-hexahydroquinoline-3-carboxylate

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