VCP 171 Size:2mg solid Epub 2015 Sep 2
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VCP 171 Size:2mg solid Epub 2015 Sep 2Adenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5. 65, binding cooperativity with NECA 0. 68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve injury model of neuropathic pain. Product information CAS Number: 1018830 99 3 Molecular
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