TL 12-186 RD9 Degrader-1 InChi: InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H

InChi: InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H

Chemical Name: 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2

Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action

The monoamine reuptake blocker brasofensine reverses akinesia without dyskinesia in MPTP-treated and levodopa-primed common marmosets

Kobayashi M

TL 12-186 RD9 Degrader-1 InChi: InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6HTL12 186 is a multikinase degrading PROTAC. Product information CAS Number: 2250025 88 6 Molecular Weight: 931. 46 Formula: C44H51ClN10O9S Chemical Name: N (2 (2 (2 (4 (4 ((5 Chloro 4 ((2 (isopropylsulfonyl)phenyl)amino)pyrimidin 2 yl)amino)phenyl)piperazin 1 yl)ethoxy)ethoxy)ethyl) 2 ((2 (2, 6 dioxopiperidin 3 yl) 1, 3 dioxoisoindolin 4 yl)amino)acetamide Smiles: