Vernakalant mesaconine 2013 Oct 24

2013 Oct 24

CZC-25146 is a potent and selective LRRK2 inhibitor

and has been suggested as an adjuvant treatment for schizophrenia

4-triazole based specific tankyrase 1/2 inhibitor

2-dimethylpropanoyl)oxy]benzenesulfonamido}phenyl)formamido]acetic acid sodium

Vernakalant mesaconine 2013 Oct 24Vernakalant HCl, also known as RSD1235, is an investigational drug for the acute conversion of atrial fibrillation. Like other class III antiarrhythmics, vernakalant blocks atrial potassium channels, thereby prolonging repolarization. It differs from typical class III agents by blocking a certain type of potassium channel, the cardiac transient outward potassium current, with increased potency as the heart rate increases. This means that it is more