Btk Polyclonal Antibody, 20ul[BT-AP01005] Enzyme-Linked Immunosorbent Assay (ELISA) Rotor capacity: 5mL×18
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Btk Polyclonal Antibody, 20ul[BT-AP01005] Enzyme-Linked Immunosorbent Assay (ELISA) Rotor capacity: 5mL×18The protein (Bruton tyrosine kinase) encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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