HSH2D Rabbit Polyclonal Antibody, 100ul Electrophoresis & Labeling This intronless gene encodes the

This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH)

The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells

The protein encoded by this gene contains a SH2 domain and a SOCS box domain

The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer

The protein encoded by this intronless gene

HSH2D Rabbit Polyclonal Antibody, 100ul Electrophoresis & Labeling This intronless gene encodes theT cell activation requires 2 signals: recognition of antigen by the T cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al. 2003