c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes SOX17 encodes a member of

SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate

intracellular N and C termini

Mutations in this gene are associated with cardiofaciocutaneous syndrome

The N-terminus is poorly conserved and may impart additional roles in developmental regulation

The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes SOX17 encodes a member ofThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a