SESN3 Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases This protein may be regulated

This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process

the mature protein downregulates fibrinolysis

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Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS)

Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect

SESN3 Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases This protein may be regulatedThis gene encodes a member of the sestrin family of stress induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC alpha serine threonine protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript