AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification Three alternatively spliced transcripts encoding

Three alternatively spliced transcripts encoding different isoforms have been described

Two alternatively spliced transcript variants encoding different isoforms are described for this gene

Mutations in this gene have been found in some patients with the CHARGE syndrome

This gene encodes a small GTP-binding protein of the Rab GTPase family

and regulation of cell shape

AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification Three alternatively spliced transcripts encodingThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR