Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels The encoded protein is primarily

The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation

Mutations in this gene have been associated with Oguchi disease

the diabetic state

and secreted

The phosphorylation of RAD17 checkpoint clamp loader component is required for the DNA-damage-induced cell cycle G2 arrest

Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels The encoded protein is primarilyThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,