CD244 Polyclonal Antibody, 50ul Buffer Solutions These proteins are basic helix-loop-helix

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

GO annotations related to this gene include calcium ion binding

and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells

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The protein encoded by this gene belongs to the peptidase C12 family

CD244 Polyclonal Antibody, 50ul Buffer Solutions These proteins are basic helix-loop-helixCD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non major histocompatibility complex (MHC) restricted killing. The interaction between NK cell and target cells via this receptor is thought to modulate NK cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.