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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesis

SKU: 97824410912

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Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Also exhibits low-fidelity DNA synthesis

The gene is ubiquitously expressed but is found in abundance in the spleen

May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites)

suggested it might play a role in the regulation of transcription

BSX (Brain Specific Homeobox) is a Protein Coding gene

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis Also exhibits low-fidelity DNA synthesisMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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