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MALT1 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) These isoforms exhibit different expression

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MALT1 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) These isoforms exhibit different expressionMALT1 has been found to be recurrently rearranged in chromosomal translocation with two other genes baculoviral IAP repeat containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus in mucosa associated lymphoid tissue lymphomas. The MALT1 paracaspase encoded by MALT1 may play a role in NF kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Description

These isoforms exhibit different expression patterns and varying levels of GEF activity

This gene encodes a nuclear protein that likely functions as a transcription factor

and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix

subfamily C

and has been shown to be a major component required for serum-dependent melanoma cell growth

MALT1 Polyclonal Antibody, 50ul Enzyme-Linked Immunosorbent Assay (ELISA) These isoforms exhibit different expressionMALT1 has been found to be recurrently rearranged in chromosomal translocation with two other genes baculoviral IAP repeat containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus in mucosa associated lymphoid tissue lymphomas. The MALT1 paracaspase encoded by MALT1 may play a role in NF kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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