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c-Abl Rabbit Polyclonal Antibody, 100ul Pathway and Network Analysis This gene encodes a cytosolic

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c-Abl Rabbit Polyclonal Antibody, 100ul Pathway and Network Analysis This gene encodes a cytosolicThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation,

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Description

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation

tissue specificity:Appears to be expressed ubiquitously

Among its related pathways are Creation of C4 and C2 activators and Regulation of actin dynamics for phagocytic cup formation

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients

c-Abl Rabbit Polyclonal Antibody, 100ul Pathway and Network Analysis This gene encodes a cytosolicThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation,

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