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LAX1 Polyclonal Antibody, 100ul Biochemical Reagents and a conserved C-terminal SH2

SKU: 9647764228

4.8
USD123.75 USD172.75

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LAX1 Polyclonal Antibody, 100ul Biochemical Reagents and a conserved C-terminal SH2Negatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in

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Description

and a conserved C-terminal SH2 domain

and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins

suitable for most glass and plastic culture medium storage bottles

a pseudogene of SRSF11 has been found on chromosome 12

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

LAX1 Polyclonal Antibody, 100ul Biochemical Reagents and a conserved C-terminal SH2Negatively regulates TCR (T cell antigen receptor) mediated signaling in T cells and BCR (B cell antigen receptor) mediated signaling in B cells.,induction: Up regulated in T cells following TCR engagement.,PTM: Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit: When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity: Expressed in

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