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Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection Defects in ITGA7 are associated

SKU: 96266709575

4.1
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Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection Defects in ITGA7 are associatedVAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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Description

Defects in ITGA7 are associated with congenital myopathy

and requires vesicular acidification to bind lipid antigens

A study of over-expression of this collagen in mice

SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies

and proteolysis

Vav3 Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection Defects in ITGA7 are associatedVAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide free states of these GTPases. Alternatively spliced transcript variants encoding

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