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MIB2 Polyclonal Antibody, 50ul Yeast Expression The encoded protein is believed

SKU: 96233482623

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SEK162.00 SEK198.00

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MIB2 Polyclonal Antibody, 50ul Yeast Expression The encoded protein is believedE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result

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Description

The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle

active MAP3K8 is released by proteasome-dependent degradation of NFKB1/p105

SPSB4 and RAB40C

In humans| this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes

POLD3 encodes the 66-kDa subunit of DNA polymerase delta

MIB2 Polyclonal Antibody, 50ul Yeast Expression The encoded protein is believedE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result

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