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TNPO1 Polyclonal Antibody, 100ul Enzymes This enzyme is essential for

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TNPO1 Polyclonal Antibody, 100ul Enzymes This enzyme is essential forThis gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

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Description

This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells

Homozygous mutations at highly conserved position of RAD54B were observed in human primary lymphoma and colon cancer

Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane| leading to its presence in the cytoplasm

Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome

TNPO1 Polyclonal Antibody, 100ul Enzymes This enzyme is essential forThis gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins.

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