Stat5a/b(Phospho Ser726/731) Polyclonal Antibody, 20ul Peptide Synthesis While all three are adapter

While all three are adapter proteins in signal transduction pathways| the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

some members of which are clustered together on chromosome 12q13

and some transcript variants of this gene are specifically expressed in glioma cells

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules

Stat5a/b(Phospho Ser726/731) Polyclonal Antibody, 20ul Peptide Synthesis While all three are adapterThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM CSF, erythropoietin,