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CAN7 Polyclonal Antibody, 20ul Pipette Filler stimulating translocation to the nucleus

SKU: 95391912740

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CAN7 Polyclonal Antibody, 20ul Pipette Filler stimulating translocation to the nucleusCalpains are ubiquitous, well conserved family of calcium dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function

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Description

stimulating translocation to the nucleus where it forms homo- or heterooligomers with other members of the microphthalmia transcription factor (MiTF) subfamily and resulting in up-regulation of autophagosomes and lysosomes

It was shown that the activation occurs through phosphatidylinositol 3-kinase

indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases

cerevisiae Cox19 protein may play a role in metal transport to the mitochondrial intermembrane space and assembly of complex IV of the mitochondrial respiratory chain

Its sterilization guarantees safety and efficiency in any experiment

CAN7 Polyclonal Antibody, 20ul Pipette Filler stimulating translocation to the nucleusCalpains are ubiquitous, well conserved family of calcium dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function

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