CLCN1 Polyclonal Antibody, 50ul Culture Media The PCAF histone acetylase complex

The PCAF histone acetylase complex

have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al

Isoform 2 is a more general and stronger transcriptional coactivator

Alternative splicing results in multiple tr

Defects in this gene have been linked to infertility

CLCN1 Polyclonal Antibody, 50ul Culture Media The PCAF histone acetylase complexThe CLCN family of voltage dependent chloride channel genes comprises nine members (CLCN1 7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant