FA2H Polyclonal Antibody, 20ul Peptide Modification Component of the probable ECS(SPSB4)

Component of the probable ECS(SPSB4) complex with the substrate recognition component SPSB4

Multiple different transcript variants are generated by alternate splicing

more specifically

which always presents with retinal degeneration (SCA7)

AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate

FA2H Polyclonal Antibody, 20ul Peptide Modification Component of the probable ECS(SPSB4)This gene encodes a protein that catalyzes the synthesis of 2 hydroxysphingolipids, a subset of sphingolipids that contain 2 hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2 hydroxylation of the N acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy