UNC5D Polyclonal Antibody, 20ul Yeast Expression Mutations in MYBPC3 are one

Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy

GIMAP5 encodes GTPase IMAP family member 5 belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins

Role in cell fate determination

Additional alternatively spliced transcript variants of this gene have been described| but their full-length nature is not known

This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene

UNC5D Polyclonal Antibody, 20ul Yeast Expression Mutations in MYBPC3 are oneReceptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.,PTM: Phosphorylated on cytoplasmic tyrosine residues.,PTM: