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CD158e Polyclonal Antibody, 100ul Multi-Layer Cell Culture System Members of this family have

SKU: 94064088915

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CD158e Polyclonal Antibody, 100ul Multi-Layer Cell Culture System Members of this family haveKiller cell immunoglobulin like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,

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Description

Members of this family have three conserved domains: an N-terminal homology domain

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein

both of which have a role in bone cell biology

Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5

Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete

CD158e Polyclonal Antibody, 100ul Multi-Layer Cell Culture System Members of this family haveKiller cell immunoglobulin like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,

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