VEGF Receptor 2(Phospho-Tyr1212) Rabbit Polyclonal Antibody, 100ul Polyclonal Antibodies Interleukin 12 is a disulfide-linked

Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene

This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity

It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions

The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex

1996 [PubMed 8663286])

VEGF Receptor 2(Phospho-Tyr1212) Rabbit Polyclonal Antibody, 100ul Polyclonal Antibodies Interleukin 12 is a disulfide-linkedVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors