HNF1A Polyclonal Antibody, 100ul Funnels Two alternatively spliced transcripts encoding

Two alternatively spliced transcripts encoding different isoforms have been described for GAB2

CCT8 encodes the theta subunit of the CCT chaperonin

and may act as a DNA unwinding enzyme

CYP4Z1 is part of a cluster of cytochrome P450 genes on chromosome 1p33

The protein localizes to the cytoplasm

HNF1A Polyclonal Antibody, 100ul Funnels Two alternatively spliced transcripts encodingThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different