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Phospho-Akt (S473) mouse Monoclonal Antibody(6F8), 100ul Buffer Solutions ABHD11 is deleted in Williams

SKU: 92861703076

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Phospho-Akt (S473) mouse Monoclonal Antibody(6F8), 100ul Buffer Solutions ABHD11 is deleted in WilliamsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

ABHD11 is deleted in Williams syndrome

a basic domain

The encoded protein binds DNA as a monomer

CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953

The protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle

Phospho-Akt (S473) mouse Monoclonal Antibody(6F8), 100ul Buffer Solutions ABHD11 is deleted in WilliamsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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