MER/TYRO3(Phospho-Tyr753/Tyr685) Polyclonal Antibody, 50ul Cytokines Alternative splicing of UMOD results

Alternative splicing of UMOD results in multiple transcript variants

Pseudogenes of MARK4 are located on both the short and long arm of chromosome 3

Containing six ANK repeats and thirty-seven exons

A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors

Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus

MER/TYRO3(Phospho-Tyr753/Tyr685) Polyclonal Antibody, 50ul Cytokines Alternative splicing of UMOD resultsThis gene is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).