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Tau Polyclonal Antibody, 50ul[BT-AP08843] Dry Bath Accumulation of EXPAND1/MUM1 at damaged

SKU: 92362114686

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Tau Polyclonal Antibody, 50ul[BT-AP08843] Dry Bath Accumulation of EXPAND1/MUM1 at damagedMAPT encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico

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Description

Accumulation of EXPAND1/MUM1 at damaged DNA sites is thought to modify the structure of the chromatin and allow access to other DNA repair factors

GO annotations related to this gene include protein homodimerization activity and intracellular calcium activated chloride channel activity

The MBP tag also promotes proper folding of the attached protein

|PTM:Tyrosine phosphorylated in response to IFN-alpha

the encoded protein does not associate with intracellular G-proteins

Tau Polyclonal Antibody, 50ul[BT-AP08843] Dry Bath Accumulation of EXPAND1/MUM1 at damagedMAPT encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico

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