ORC1 Polyclonal Antibody, 100ul Syringe Filter This protein functions in the

This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling

Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle

and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs

The protein is phosphorylated in a cell-cycle dependent manner

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

ORC1 Polyclonal Antibody, 100ul Syringe Filter This protein functions in theORC1 encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. Origin recognition complex subunit 1 contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.